We are a virtual clinic licensed in Texas, New York, California, Washington, New Mexico, and Iowa, offering advanced support for individuals experiencing treatment-resistant or refractory depression.
At Polished Mind Psychiatry, we specialize in helping individuals who have not responded to traditional treatments. We use advanced therapies and a compassionate approach to help you find relief.
Refractory depression is a form of major depressive disorder that does not respond adequately to at least two different antidepressant medications, taken at the right dose and duration. Individuals with this condition often experience ongoing sadness, lack of motivation, fatigue, and difficulty functioning in daily life.
The causes of treatment-resistant depression can vary and may include biological, genetic, or psychological factors. Understanding these underlying issues is the first step toward finding a treatment that works.
If these symptoms continue despite trying multiple medications or therapies, you may be experiencing treatment-resistant depression.
Our evaluation process includes a detailed review of your mental health history, medications you have tried, treatment responses, and any co-occurring conditions such as anxiety, ADHD, or PTSD. We assess your symptoms, medical background, and emotional patterns to understand the full picture. In some cases, we may recommend additional tools like GeneSight testing to personalize your treatment plan.
At Polished Mind Psychiatry, we offer a range of advanced and evidence-based options for individuals with treatment-resistant depression. Each treatment plan is customized to meet your unique needs and may include the following:
We understand the toll that refractory depression can take on your life. Our team is here to provide the guidance and care you need to move forward.
Spravato (esketamine) is an FDA-approved nasal spray treatment for adults with treatment-resistant depression. It works differently from traditional antidepressants and may provide rapid relief from symptoms. Spravato is used under close supervision and as part of a complete treatment plan that includes medication management and therapy.
IV infusion therapy delivers fast-acting antidepressant effects for individuals who have not responded to oral medications. This treatment is administered in a safe and controlled setting, helping to improve mood and energy levels within hours to days. It can be an effective option when other treatments have failed.
GeneSight testing analyzes your genetic makeup to predict how you may respond to certain medications. For individuals with treatment-resistant depression, this can help reduce the trial-and-error process of finding the right medication. The test is simple and can be done virtually through our clinic.
