GeneSight Testing

We proudly offer GeneSight testing through our virtual clinic, licensed in Texas, New York, California, Washington, New Mexico, and Iowa.

Personalized care starts at the genetic level.

At Polished Mind Psychiatry, we believe that mental health treatment should never be one-size-fits-all. GeneSight® testing allows us to take a more targeted approach by analyzing how your DNA may influence your response to psychiatric medications. This powerful tool helps reduce the trial-and-error process and allows our clinicians to develop a treatment plan that aligns with your unique genetic makeup.

What Is GeneSight?

GeneSight is a type of pharmacogenomic testing that looks at how your genes affect the way your body processes and responds to certain medications used to treat conditions like:

Depression
Anxiety
ADHD
Bipolar disorder
Other psychiatric conditions

This test helps your provider identify which medications may be more effective for you and which may be more likely to cause side effects—based on your genetic profile.

GeneSight is especially helpful for individuals who:

Have not found relief after trying multiple medications
Have experienced significant side effects
Are beginning psychiatric treatment and want a more personalized starting point

How Does GeneSight Work?

The GeneSight test requires a simple cheek swab, which can be completed at home or in a provider’s office. The sample is then sent to a certified laboratory for analysis.

The test evaluates key genetic markers across three key areas:

Pharmacokinetics – How your body absorbs, breaks down, and clears medications
Pharmacodynamics – How your brain receptors and pathways may interact with different drugs
Gene-drug interactions – How your genes may influence the effectiveness or risk of side effects from specific medications

Once the lab processes your sample, a detailed report is generated for your provider. Medications are categorized into groups such as:

Use as directed
Use with caution
Use with increased monitoring

This information supports informed, data-driven decisions when selecting or adjusting psychiatric medications.

Benefits of GeneSight Testing

GeneSight helps improve the precision and effectiveness of psychiatric care. With insights from your DNA, your provider can create a personalized treatment plan that is:

More likely to reduce symptoms faster
Less likely to cause adverse reactions
Better aligned with your body’s natural response to medication
Designed to reduce the frustration of trial and error
Especially useful in treatment-resistant or complex cases

Instead of guessing which medication might work, GeneSight allows us to use science-backed data to guide your care, resulting in a more efficient and empowering treatment experience.

How Can GeneSight Improve the Care I Receive?

GeneSight testing can enhance the accuracy and effectiveness of psychiatric treatment by identifying how your body may respond to specific medications. This genetic insight helps your provider choose medications that are more likely to work well for you and cause fewer side effects. For individuals with complex treatment histories or medication-resistant conditions, GeneSight offers much-needed clarity. Instead of relying on trial and error, your care becomes more personalized, efficient, and targeted, leading to faster symptom relief, better medication tolerance, and improved long-term outcomes.

To find out if GeneSight testing is right for you, schedule a virtual consultation with Polished Mind Psychiatry today.